Our new Apparent+ tissue clearing procedure is the one strategy that delipidates samples without any improve in morphology and with small effect on structural integrity.
Megatome is actually a vibrating microtome designed to portion a wide variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome permits significant-throughput tissue sectioning with uniform surface profile, and also negligible tissue destruction and data loss.
Request a quotation or demo Uniformly segment massive tissues & sample arrays Megatome is the only microtome which will segment samples as significant as intact nonhuman primate and human organs, which makes it a must have for fields for instance neuropathology.
Functioning the CLI directly from a Gradle process will not be at this time supported. A distribution need to be developed by using gradlew :j2d-cli:distZip to create a zip file that contains everything necessary to operate.
SE uses a rotational electric subject to disperse highly electromobile molecules (including antibodies or surfactant micelles) through a porous sample without having detrimental electrically billed structures inside the tissue. This permits two-four working day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely clear. This allows light-weight penetration into your sample and ensures the acquisition of higher-resolution, in-concentrate picture info.
Megatome can be a novel microtome that permits for high-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue problems and data loss.
It’s the perfect time to up grade your microtome to Megatome. With correct high-frequency slicing for an unmatched number of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied apps.
Completely delipidate whole mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for many rounds of processing.
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Our novel Protect tissue preservation system sorts intramolecular bonds applying polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.